The Genetic Architecture of Type 1 Diabetes

The Genetic Architecture of Type 1 Diabetes

Type 1 diabetes (T1D) is classically characterised by the clinical need for insulin, the presence of disease-associated serum autoantibodies, and an onset in childhood. The disease, as with other autoimmune diseases, is due to the interaction of genetic and non-genetic effects, which induce a destructive process damaging insulin-secreting cells. In this review, we focus on the nature of this in...

the investigation of the relationship between type a and type b personalities and quality of translation

چکیده ندارد.

The genetic basis for type 1 diabetes.

BACKGROUND Type 1 diabetes (T1D) is characterized by autoimmune destruction of insulin-producing beta-cells in the pancreas resulting from the action of environmental factors on genetically predisposed individuals. The increasing incidence over recent decades remains unexplained, but the capacity of identifying infants at highest genetic risk has become an increasing requirement for potential t...

Genetic Determinants of Type 1 Diabetes Mohamed

Type 1 diabetes: a genetic Pandora's box?